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Eye: M766/90

EYE

SPICES No. M766/90

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GROSS DESCRIPTION
This is exhibit displays eye with retinoblastoma. There is malignant tumor arising from the retina growing into subretinal spaces and vitreous.
HISTOPATHOLOGY DESCRIPTION
Retinoblastoma is show highly cellular tumours arranged in sheets and some in trabeculae pattern. The cells are small, round and blue with scanty cytoplasm. Flexner-Wintersteiner rosettes is seen. Calcification and perivascular necrosis also appreciated.
DIAGNOSIS
Retinoblastoma

Brain

BRAIN IN LUXOL FAST BLUE

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Brain

BRAIN

SPICES No. M42/82

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GROSS DESCRIPTION
The exhibit displays presence of large supratentorial tumor arising in and occupying the lateral ventricle causing midline shift. Areas of central degenerated cystic changes observed.
HISTOPATHOLOGY DESCRIPTION
Section shows hypercellular tumour cells with sharply demarcated border. The cells are monomorphic with speckled chromatin pattern. Perivascular pseudorosettes and ependymal rosettes also appreciated.
DIAGNOSIS
Ependymoma

Brain

BRAIN

SPICES No. M37/82

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GROSS DESCRIPTION
The exhibit displays brain with hydrocephalus. There is remarkable unilateral enlarged and dilated lateral ventricle. The adjacent brain parenchyma appear normal.
DIAGNOSIS
Hydrocephalus
QUIZ
Causes of unilateral hydrocephalus

Brain

BRAIN

SPICES No. M36/82

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GROSS DESCRIPTION
The exhibit displays brain with few foci of metastatic malignant tumor infiltrating the brain parenchyma. It shows variable size of metastatic foci with heterogenous tan to brownish surface.
HISTOPATHOLOGY DESCRIPTION
Section shows infiltrating malignant cells arranged in gland producing mucin. The cells displaying mild pleomorphism, round to oval nuclei shaped and moderate amount of eosinophilic cytoplasm. Adjacent glial tissue noted.
DIAGNOSIS
Metastasis mucin secreting adenocarcinoma

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