TOE

SPICES No. M1089/94

Front
Left
BACK
RIGHT

GROSS DESCRIPTION
The exhibit displays a toe with presence of exophytic fungating malignant lesion arising from the skin. The mass shows irregular hyperkeratotic scaly plaque surface.
HISTOPATHOLOGY DESCRIPTION
Squamouos cell carcinoma show malignant epithelium with evidence of squamous differentiation. These include the presence of individual keratinization, intercellular bridges, and keratin pearl.
DIAGNOSIS
Squamous cell carcinoma
QUIZ
Chronic cutaneous ulcers pose a risk for squamous cell carcinoma development.

SKIN

SPICES No. M247/84

Front
Left
BACK
RIGHT

GROSS DESCRIPTION
The exhibit displays exophytic fungating malignant lesion arising from the skin. The mass shows irregular hyperkeratotic scaly plaque surface.
HISTOPATHOLOGY DESCRIPTION
Squamous cell carcinoma show malignant epithelium with evidence of squamous differentiation. These include the presence of individual keratinization, intercellular bridges, and keratin pearl.
DIAGNOSIS
Squamous cell carcinoma
QUIZ
The most important causative agent of cutaneous squamous cell carcinoma is UV light

Dermatology System

Skin is the largest organ in the body and commonly affected by a wide range of pathology. The disease process not only limited to primary disorder of the skin but involve cutaneous manifestation of systemic disease. Primary skin disorder are common entailing inflammatory and neoplastic disease. Viral illneses for example measles are associated with characteristic skin rashes and many autoimmune and vasculitic disorder may present with skin manifestation.