The exhibit displays a benign exophytic lesion arising from the skin.
Squamous papilloma shows papillary architecture with prominent fibrovascular cores. They exhibit proliferation of stratified squamous epithelium with variable hyperkeratosis or parakeratosis.
Squamous papilloma
The exhibit displays exophytic fungating malignant lesion arising from the skin. The mass shows irregular hyperkeratotic scaly plaque surface.
Squamous cell carcinoma show malignant epithelium with evidence of squamous differentiation. These include the presence of individual keratinization, intercellular bridges, and keratin pearl.
Squamous cell carcinoma
The exhibit displays a fungating blackish mass (45x40x40mm) at the tip of the finger. The mass has infiltrated deep into the bone and surrounding soft tissue. The surgical margin is free from tumour.
Melanoma shows infiltrating tumour cells arranged in small nest and sheets. The cells are markedly pleomorphic, round to oval nulcei, coarse chromatin with large prominent nucleoli and moderate amount of eosinophilic cytoplasm. Mitosis easily seen including atypical form. No neurotization identified.
Melanoma
Pesakit lelaki berumur 28 tahun dengan lesi berpigmen pada jari kanan.
Diagnosis: Melanoma
Melanoma adalah sejenis kanser kulit yang berasal daripada sel melanosit (tahi lalat). Iaitu, sejenis sel yang menghasilkan melanin. Ia merupakan kanser kulit yang agresif dan berpotensi merabak ke kawasan lain sekiranya tidak dirawat awal. Melanoma sering dikaitkan dengan pendedahan yang berlebihan kepada sinaran ultraviolet.
Tanda-tanda amaran melanoma:
Asimetri - Tompok pada kulit tidak sama.
Sempadan - Tepinya tidak sekata, bergerigi, kabur atau bertakuk.
Warna - Warna tidak konsisten.
Diameter - Diameter tempat adalah lebih daripada 6 mm.
Berkembang - Tempat itu berubah warna, saiz atau bentuk.
The exhibit displays large intradermal tumour. It shows fairly well circumscribed border with tan surface. The overlying skin shows ulceration.
Dermatofibrosarcoma protuberance shows intradermal spindle cell lesion arranged in storiform to whorled pattern, with some area infiltrate the fat tissue. The cells exhibit monomorphic nuclei and ovoid to elongated with abundant and eosinophilic cytoplasm. Mitotic activity is seen.
Dermatofibrosarcoma protuberance
The exhibit displays exophytic fungating malignant lesion arising from the skin. The mass shows irregular hyperkeratotic scaly plaque surface.
Squamous cell carcinoma show malignant epithelium with evidence of squamous differentiation. These include the presence of individual keratinization, intercellular bridges, and keratin pearl.
Squamous cell carcinoma
Industrial carcinogenic agents for squamous cell carcinoma include tars
